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General Information

mtDNA (mitochondrial DNA) is passed down from mother to child. Men have their mother's mtDNA, but do not pass it on to their children. 30 major maternal lineages (haplogroups) have been identified worldwide. The mtDNA test determines which one of the 30 maternal lineages you belong to and provides the broad geographic region throughout which the lineage is found (Example: Africa, Europe, Middle East).

The Maternal Line Analysis test may be used to support or disprove a relationship within the same direct maternal lineage. Maternal Line Analysis testing utilizes the portion of the DNA known as mitochondrial DNA (mtDNA), the DNA that is passed from mothers to each child, but which only female children continue to pass down. Therefore, participants may be either male or female, although this test may not be used to evaluate the paternal lineage.

The Maternal Line Analysis testing takes advantage of a special form of DNA that is passed from mother to biological child through the egg. Each of us carries virtually an exact copy of our mother's mtDNA. Therefore, all of our siblings and direct maternal relatives also have identical mtDNA sequences. Thus mtDNA is a valuable investigative tool for researching direct maternal line ancestry.

Sequences portions of the mtDNA known as hypervariable regions. These sequences are then compared to the revised Cambridge Reference Sequence (rCRS). The rCRS is the reference standard against which all mtDNA sequences are compared. Your final report, Certificate of Mitochondrial DNA Analysis, will include a table showing the differences found between your profile and the rCRS. All remaining base pairs can be understood to be identical to the rCRS. Additionally, we provide a complimentary mtDNA haplogroup prediction identifying a geographic population group serving as an indication of deep ancestral origins.

Please contact your customer service representative for further information.

Fees

590.00

Specimen Requirements

Buccal swab; 10cc Lavender

Turnaround Time

4-7 days, up to 10 days for complex analysis

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